Obat untuk Penghilang Rasa Sakit (Pain Killer) | ||||||||||
Nama Obat | AAP approved?* | Kategori Risiko Kehamilan** | Risiko Menyusui** | Notes | ||||||
Acetaminophen (Tylenol) | Approved | B | L1 | |||||||
Aspirin | Caution | C (1st, 2nd trim.) D (3rd trim.) | L3 | |||||||
Azapropazone (Rheumox) | Approved | - | L2 | |||||||
Butalbital (Fioricet, Fiorinal, Bancap, Two-dyne) | NR | D | L3 | |||||||
Butorphanol (Stadol) | Approved | B (1st, 2nd trim.) D (3rd trim.) | L3 | |||||||
Celecoxib (Celebrex)) | NR | C | L2 | |||||||
Codeine (in Tylenol #3, #4) | Approved | C | L3 | |||||||
Colchicine | Approved | D | L4 | |||||||
Diclofenac (Cataflam, Voltaren) | NR | B | L2 | |||||||
Fentanyl (Sublimaze) | Approved | B | L2 | |||||||
Flurbiprofen (Ansaid, Froben, Ocufen) | NR | B (1st, 2nd trim.) C (3rd trim.) | L2 | |||||||
Hydrocodone (Lortab, Vicodin) | NR | B | L3 | |||||||
Hydromorphone (Dilaudid) | NR | C | L3 | |||||||
Ibuprofen (Advil, Nuprin, Motrin, Pediaprofen) | Approved | B (1st, 2nd trim.) D (3rd trim.) | L1 | |||||||
Indomethacin (Indocin) | Approved | B (1st, 2nd trim.) D (3rd trim.) | L3 | |||||||
Ketorolac (Toradol, Acular) | Approved | B (1st, 2nd trim.) D (3rd trim.) | L2 | |||||||
Meperidine (Demerol) | Approved | B | L2; L3 early postpartum | |||||||
Methadone (Dolophine) | Approved | B | L3 | |||||||
Morphine (Duramorph, Infumorph, Epimorph, MS Contin) | Approved | B | L3 | |||||||
Nalbuphine (Nubain) | NR | B | L2 | |||||||
Naproxen (Anaprox, Naprosyn, Naproxen, Aleve) | Approved | B | L3; L4 for chronic use | |||||||
Nefopam (Acupan) | Approved | - | NR | |||||||
Oxycodone (Tylox, Percodan,Oxycontin, Roxicet, Endocet, Roxiprin, Percocet) | NR | B | L3 | |||||||
Pentosan polysulfate (Elmiron) | NR | B | L2 | |||||||
Piroxicam (Feldene) | Approved | B | L2 | |||||||
Propoxyphene (Darvocet N, Propacet, Darvon) | Approved | C | L2 | |||||||
Rofecoxib (Vioxx) | ||||||||||
Secobarbital (Seconal) | Approved | D | L3 | |||||||
Tolmetin (Tolectin) | Approved | C | L3 | |||||||
Tramadol HCL (Ultram, Ultracet) | NR | C | L3 | |||||||
Valdecoxib (Bextra) | ||||||||||
* Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001.
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- Aspirin use is discouraged in children and nursing mothers due to the risk of Reye’s syndrome and internal bleeding.
- Fioricet (Fiorinal, Bancap, Two-dyne) contains acetaminaphen or asprin, caffeine, and butalbital. Per Hale, baby should be observed for sedation.
- Hale suggests weakened or premature infants be observed for sedation and apnea.
- Hale suggests newborns be observed for sedation, apnea, constipation.
- Per Hale, use of frequent, higher dose may result in infant sedation.
- Per Hale, Meperidine use during labor or early postpartum has been associated with sedation, poor sucking reflex, and neurobehavioral delay in infants.
- Per Hale, observe infant for sedation, respiratory depression, addiction, withdrawal syndrome.
- Per Hale, higher doses may result in infant sedation.
- Per Hale, should be used with caution due to its long half-life and its effect on baby’s cardiovascular system, kidneys and GI tract; short-term, infrequent or occasional use is not necessarily incompatible with breastfeeding.
- Roxicet, Endocet, Roxiprin, Percocet also contain acetaminophen. Per Hale, observe infant for sedation.
- Per Hale, observe infant for sedation.
- Per Hale, observe infant for GI cramping, distress, diarrhea.
- Per Hale, observe infant for sedation.
- Per Hale, observe infant for sedation.
Non-steroidal anti-inflammatory analgesics (NSAIDs) [more] | ||||
Nama Generik | Nama Dagang | AAP approved?* | Kategori Risiko Kehamilan** | Risiko Menyusui** |
Azapropazone (apazone) | Rheumox | Approved | - | L2 |
Dipyrone (banned in the US & UK) | - | Approved | - | NR |
Flufenamic acid | - | Approved | - | NR |
Ibuprofen | Advil, Nuprin, Motrin, Pediaprofin | Approved | B (1st, 2nd trim.) D (3rd trim.) | L1 |
Indomethacin | Indocin | Approved | B (1st, 2nd trim.) D (3rd trim.) | L3 |
Ketorolac | Toradol, Acular | Approved | B (1st, 2nd trim.) D (3rd trim.) | L2 |
Mefenamic acid | Ponstan, Ponstel | Approved | - | NR |
Naproxen | Anaprox, Naprosyn, Naproxen, Aleve | Approved | B | L3 L4 (for chronic use) |
Phenylbutazone | Butazolidine | Approved | - | NR |
Piroxicam | Feldene | Approved | B | L2 |
Suprofen | Profenal | Approved | - | NR |
Tolmetin | Tolectin | Approved | C | L3 |
Steroid | [contents] | |||
Methylprednisolone [ high dosage methylprednisolone] | Solu-Medrol, Depo-Medrol, Medrol | Approved | C | L2 |
Prednisolone | - | Approved | C | L2 |
Prednisone | Deltasone, Meticorten, Orasone | Approved | C | L2 |
Obat Asma | [contents] | |||
Dyphylline | Dilor, Lufyllin, Dyphylline | Approved | C | L3 |
Terbutaline | Bricanyl, Brethine | Approved | B | L2 |
Theophylline | Aminophylline, Quibron, Theo-Dur | Approved | C | L3 |
Analgetik Narkotik [more] | ||||
Butorphanol | Stadol | Approved | B (1st, 2nd trim.) D (3rd trim.) | L3 |
Codeine | Tylenol #3, #4 | Approved | C | L3 |
Fentanyl | Sublimaze | Approved | B | L2 |
Meperidine | Demerol | Approved | B | L2 L3 (if used early postpartum) |
Methadone | Dolophine | Approved | B | L3 |
Morphine | Morphine | Approved | B | L3 |
Propoxyphene | Darvocet N, Propacet, Darvon | Approved | C | L2 |
Obat Batuk | |||
Nama Obat | AAP approved?* | Risiko Menyusui** | |
Codeine | yes | L3 (moderately safe) | |
Dextromethorphan | not reviewed | L1 (safest) | |
Guaifenesin | not reviewed | L2 (safer) | |
Dekongestan (Obat Pilek) | |||
Nama Obat | AAP approved?* | Risiko Menyusui** | |
Phenylephrine | not reviewed | L3 (moderately safe) | |
Pseudoephedrine (Sudafed, Actifed) | yes | L3 (moderately safe) for acute use L4 (possibly hazardous) for chronic use due to potential for decreasing milk supply | |
* Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001. ** Per Medications’ and Mothers’ Milk by Thomas Hale, PhD (2006 edition) | |||
Nasal Sprays (Spray Hidung) | |||
Nama Obat | AAP approved?* | Risiko Menyusui** | |
Beclomethasone (Vanceril, Beclovent, Beconase, Vancenase) | not reviewed | L2 (safer) | |
Cromlyn sodium (Nasalcrom) | not reviewed | L1 (safest) | |
Fluticasone (Flonase) | not reviewed | L3 (moderately safe) | |
Mometasone (Nasonex) | not reviewed | L3 (moderately safe) | |
Phenylephrine (in some forms of Sinex and Neo-Synephrine) | not reviewed | L3 (moderately safe) | |
Triamcinolone Acetonide (Nasacort) | not reviewed | L3 (moderately safe) | |
Antihistamin (Anti Alergi) | |||
Nama Obat | AAP approved?* | Risiko Menyusui** | |
Brompheniramine | not reviewed | L3 (moderately safe) | |
Chlorpheniramine (Chlor-Trimeton) CTM | not reviewed | L3 (moderately safe) | |
Cetirizine (Zyrtec) | not reviewed | L2 (safer) | |
Dexbrompheniramine maleate with d-isoephedrine | yes | not reviewed | |
Diphenhydramine (Benadryl) | not reviewed | L2 (safer) | |
Doxylamine | not reviewed | L4 (possibly hazardous) | |
Fexofenadine (Allegra) | yes | L3 (moderately safe) | |
Loratadine (Claritin) | yes | L2 (safer) | |
Terfenadine (Seldane) | yes | not reviewed | |
Triprolidine (Actidil, Actifed) | yes | L1 (safest) | |
* Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001. ** Per Medications’ and Mothers’ Milk by Thomas Hale, PhD (2002 edition) | |||